Lactic acid as a systemic product and biomarker of physical load

This paper presents an up-to-date review of research data on the specific features lactic acid metabolism and its role as effector vital regulatory mechanisms. Lactic is alpha-hydroxy monocarboxylic acid. Physical loads submaximal intensity some diseases can cause dramatic increase content in body fluids. The excessive lactate removed from working muscle either metabolized by other tissues or excreted human body. Alteration lactate-pyruvate balance one main markers development cardiac hypertrophy failure. redistribution between cells producing it that metabolize to maintain a stable pH level hold since this compound important energy source well quantification used assess general physical capabilities body, load rate recovery rehabilitation. Specialized proteins, which refer group monocarboxylate transporters, are involved excretion absorption cells. presence various types transporters cell membranes differ affinity direction transport ensures rapid throughout regulates according physiological needs. Efficient transfer different essential, given participation several As effector, regulation angiogenesis, differentiation myosatellitocytes, regeneration fibers, polarization macrophages course inflammatory processes. Besides, participates epigenetic mechanisms tissue regulation. Therefore, key metabolites